Targeted Deletion of the Mouse α2 Nicotinic Acetylcholine Receptor Subunit Gene (Chrna2) Potentiates Nicotine-Modulated Behaviors

Baseline and nicotine-modulated behaviors were assessed in mice harboring a null mutant allele of the nicotinic acetylcholine receptor (nAChR) subunit gene α2 (Chrna2). Homozygous Chrna2(−/−) mice are viable, show expected sex and Mendelian genotype ratios, and exhibit no gross neuroanatomical abnor...

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Autori principali: Lotfipour, Shahrdad, Byun, Janet S., Leach, Prescott, Fowler, Christie D., Murphy, Niall P., Kenny, Paul J., Gould, Thomas J., Boulter, Jim
Natura: Artigo
Lingua:Inglês
Pubblicazione: Society for Neuroscience 2013
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Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3831006/
https://ncbi.nlm.nih.gov/pubmed/23637165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4731-12.2013
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