Triene prostaglandins: Prostacyclin and thromboxane biosynthesis and unique biological properties

Platelets enzymatically convert prostaglandin H(3) (PGH(3)) into thromboxane A(3). Both PGH(2) and thromboxane A(2) aggregate human platelet-rich plasma. In contrast, PGH(3) and thromboxane A(3) do not. PGH(3) and thromboxane A(3) increase platelet cyclic AMP in platelet-rich plasma and thereby: (i)...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Needleman, Philip, Raz, Amiram, Minkes, Mark S., Ferrendelli, James A., Sprecher, Howard
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1979
Fag:
Biological Sciences: Medical Sciences
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC383100/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/218223/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.76.2.944
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