Gender Difference in Cisplatin-Induced Nephrotoxicity in a Rat Model: Greater Intensity of Damage in Male Than Female

BACKGROUND: Nephrotoxicity and hepatotoxicity are side effects of Cisplatin (CP) therapy. OBJECTIVES: We investigated the role of gender in CP-induced nephrotoxicity and hepatotoxicity. MATERIALS AND METHODS: Low dose of CP (1 mg/kg/day; ip) was administered daily to male and female Wistar rats for...

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Detalhes bibliográficos
Main Authors: Nematbakhsh, Mehdi, Ebrahimian, Shadi, Tooyserkani, Mona, Eshraghi-Jazi, Fatemeh, Talebi, Ardeshir, Ashrafi, Farzaneh
Formato: Artigo
Idioma:Inglês
Publicado em: Kowsar 2013
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3830908/
https://ncbi.nlm.nih.gov/pubmed/24282792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5812/numonthly.10128
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