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Opiates and enkephalins inhibit synthesis of gangliosides and membrane glycoproteins in mouse neuroblastoma cell line N4TG1.

When mouse neuroblastoma clonal cell line N4TG1 cells were cultured in the presence of opiates or enkephalins, in the range 10(-6)-10(-10) M for 24 hr, a dose-dependent inhibition of the incorporation of [3H]glucosamine and [14C]-galactose into sialoglycosphingolipids and glycoproteins was observed....

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Publicat a:Proc Natl Acad Sci U S A
Autors principals: Dawson, G, McLawhon, R, Miller, R J
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 1979
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Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC382997/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/218211/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.76.2.605
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