Cross-Activating Invariant NKT Cells and Kupffer Cells Suppress Cholestatic Liver Injury in a Mouse Model of Biliary Obstruction

Both Kupffer cells and invariant natural killer T (iNKT) cells suppress neutrophil-dependent liver injury in a mouse model of biliary obstruction. We hypothesize that these roles are interdependent and require iNKT cell-Kupffer cell cross-activation. Female, wild-type and iNKT cell-deficient C57Bl/6...

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Main Authors: Duwaerts, Caroline C., Sun, Eric P., Cheng, Chao-Wen, van Rooijen, Nico, Gregory, Stephen H.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3829879/
https://ncbi.nlm.nih.gov/pubmed/24260285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0079702
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