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Modelling mutational and selection pressures on dinucleotides in eukaryotic phyla –selection against CpG and UpA in cytoplasmically expressed RNA and in RNA viruses

BACKGROUND: Loss of CpG dinucleotides in genomic DNA through methylation-induced mutation is characteristic of vertebrates and plants. However, these and other eukaryotic phyla show a range of other dinucleotide frequency biases with currently uncharacterized underlying mutational or selection mecha...

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Detalhes bibliográficos
Main Authors: Simmonds, Peter, Xia, Wenjun, Baillie, J Kenneth, McKinnon, Ken
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3829696/
https://ncbi.nlm.nih.gov/pubmed/24020411
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-14-610
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