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Development of an immunotherapeutic adenovirus targeting hormone-independent prostate cancer

BACKGROUND: To develop a targeting therapy for hormone-independent prostate cancer, we constructed and characterized conditionally replicating oncolytic adenovirus (Ad) equipped with mRFP (monomeric red fluorescence protein)/ttk (modified herpes simplex virus thymidine kinase). This construct was th...

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Autores principales: Kim, Jae Sik, Lee, Sang Don, Lee, Sang Jin, Chung, Moon Kee
Formato: Artigo
Lenguaje:Inglês
Publicado: Dove Medical Press 2013
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3829676/
https://ncbi.nlm.nih.gov/pubmed/24250230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S51749
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