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Shaping the Murine Macrophage Phenotype: IL-4 and cAMP Synergistically Activate the Arginase I Promoter

Arginase I is a marker of murine M2 macrophages and is highly expressed in many inflammatory diseases. The basis for high arginase I expression in macrophages in vivo is incompletely understood but likely reflects integrated responses to combinations of stimuli. Our objective was to elucidate mechan...

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Detalhes bibliográficos
Main Authors: Sheldon, Kathryn E., Shandilya, Harish, Kepka-Lenhart, Diane, Poljakovic, Mirjana, Ghosh, Arundhati, Morris, Sidney M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3829606/
https://ncbi.nlm.nih.gov/pubmed/23913966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1202102
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