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A Conserved Rod Domain Phosphotyrosine That Is Targeted by the Phosphatase PTP1B Promotes Keratin 8 Protein Insolubility and Filament Organization

Post-translational modifications are important functional determinants for intermediate filament (IF) proteins. Phosphorylation of IF proteins regulates filament organization, solubility, and cell-protective functions. Most known IF protein phosphorylation sites are serines localized in the variable...

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Detalhes bibliográficos
Main Authors: Snider, Natasha T., Park, Haewon, Omary, M. Bishr
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3829444/
https://ncbi.nlm.nih.gov/pubmed/24003221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.502724
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