Mitochondrial Localized Stat3 Promotes Breast Cancer Growth via Phosphorylation of Serine 727

Signal transducer and activator of transcription 3 (Stat3) is a key mediator in the development of many cancers. For 20 years, it has been assumed that Stat3 mediates its biological activities as a nuclear localized transcription factor activated by many cytokines. However, recent studies from this...

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Autori principali: Zhang, Qifang, Raje, Vidisha, Yakovlev, Vasily A., Yacoub, Adly, Szczepanek, Karol, Meier, Jeremy, Derecka, Marta, Chen, Qun, Hu, Ying, Sisler, Jennifer, Hamed, Hossein, Lesnefsky, Edward J., Valerie, Kristoffer, Dent, Paul, Larner, Andrew C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2013
Soggetti:
Signal Transduction
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3829438/
https://ncbi.nlm.nih.gov/pubmed/24019511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.505057
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