Mutations in SLC2A2 Gene Reveal hGLUT2 Function in Pancreatic β Cell Development

The structure-function relationships of sugar transporter-receptor hGLUT2 coded by SLC2A2 and their impact on insulin secretion and β cell differentiation were investigated through the detailed characterization of a panel of mutations along the protein. We studied naturally occurring SLC2A2 variants...

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Autors principals: Michau, Aurélien, Guillemain, Ghislaine, Grosfeld, Alexandra, Vuillaumier-Barrot, Sandrine, Grand, Teddy, Keck, Mathilde, L'Hoste, Sébastien, Chateau, Danielle, Serradas, Patricia, Teulon, Jacques, De Lonlay, Pascale, Scharfmann, Raphaël, Brot-Laroche, Edith, Leturque, Armelle, Le Gall, Maude
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2013
Matèries:
Metabolism
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3829421/
https://ncbi.nlm.nih.gov/pubmed/23986439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.469189
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