The Ccr4-Not Protein Complex Regulates the Phase of the Neurospora Circadian Clock by Controlling WHITE COLLAR Protein Stability and Activity

In the Neurospora circadian negative feedback loop, WHITE COLLAR 1 (WC-1) and WC-2 form the WC complex that activates frequency (frq) transcription. Here we show that Not1 is a WC-interacting protein and is important for maintaining WC levels. The not1 transcript displays a circadian oscillation wit...

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Bibliographic Details
Main Authors: Huang, Guocun, He, Qiyang, Guo, Jinhu, Cha, Joonseok, Liu, Yi
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2013
Subjects:
Gene Regulation
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3829413/
https://ncbi.nlm.nih.gov/pubmed/24030828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.494120
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