The Lutheran/Basal Cell Adhesion Molecule Promotes Tumor Cell Migration by Modulating Integrin-mediated Cell Attachment to Laminin-511 Protein

Cell-matrix interactions are critical for tumor cell migration. Lutheran (Lu), also known as basal cell adhesion molecule (B-CAM), competes with integrins for binding to laminin α5, a subunit of LM-511, a major component of basement membranes. Here we show that the preferential binding of Lu/B-CAM t...

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Autors principals: Kikkawa, Yamato, Ogawa, Takaho, Sudo, Ryo, Yamada, Yuji, Katagiri, Fumihiko, Hozumi, Kentaro, Nomizu, Motoyoshi, Miner, Jeffrey H.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2013
Matèries:
Glycobiology and Extracellular Matrices
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3829412/
https://ncbi.nlm.nih.gov/pubmed/24036115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.486456
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