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Nakiterpiosin Targets Tubulin and Triggers Mitotic Catastrophe in Human Cancer Cells

Agents that interfere with mitotic progression by perturbing microtubule dynamics are commonly used for cancer chemotherapy. Here, we identify nakiterpiosin as a novel anti-mitotic drug that targets microtubules. Nakiterpiosin induces mitotic arrest and triggers mitotic catastrophe in human cancer c...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Wei, Jen-Hsuan, Seemann, Joachim
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2010
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3829381/
https://ncbi.nlm.nih.gov/pubmed/21139045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-10-0305
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