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Heterochromatin Protein 1a (HP1a) Partner Specificity Is Determined by Critical Amino Acids in the Chromo Shadow Domain and C-terminal Extension

Drosophila melanogaster Heterochromatin Protein 1a (HP1a) is an essential protein critical for heterochromatin assembly and regulation. Its chromo shadow domain (CSD) homodimerizes, a requirement for binding protein partners that contain a PXVXL motif. How does HP1a select among its many different P...

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Bibliographische Detailangaben
Hauptverfasser: Mendez, Deanna L., Mandt, Rebecca E., Elgin, Sarah C. R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3829322/
https://ncbi.nlm.nih.gov/pubmed/23793104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.468413
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