O-Glycosylation as a Novel Control Mechanism of Peptidoglycan Hydrolase Activity

Acm2, the major autolysin of Lactobacillus plantarum, is a tripartite protein. Its catalytic domain is surrounded by an O-glycosylated N-terminal region rich in Ala, Ser, and Thr (AST domain), which is of low complexity and unknown function, and a C-terminal region composed of five SH3b peptidoglyca...

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Autori principali: Rolain, Thomas, Bernard, Elvis, Beaussart, Audrey, Degand, Hervé, Courtin, Pascal, Egge-Jacobsen, Wolfgang, Bron, Peter A., Morsomme, Pierre, Kleerebezem, Michiel, Chapot-Chartier, Marie-Pierre, Dufrêne, Yves F., Hols, Pascal
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2013
Soggetti:
Microbiology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3829315/
https://ncbi.nlm.nih.gov/pubmed/23760506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.470716
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