Herpesvirus-associated Ubiquitin-specific Protease (HAUSP) Modulates Peroxisome Proliferator-activated Receptor γ (PPARγ) Stability through Its Deubiquitinating Activity

The peroxisome proliferator-activated receptor γ (PPARγ) is a central regulator of adipogenesis and modulates glucose and lipid metabolism. In this study, herpesvirus-associated ubiquitin-specific protease (HAUSP) was isolated as a binding partner of PPARγ. Both endogenous and exogenous PPARγ associ...

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Detalhes bibliográficos
Main Authors: Lee, Kyeong Won, Cho, Jin Gu, Kim, Chul Min, Kang, A Young, Kim, Min, Ahn, Byung Yong, Chung, Sung Soo, Lim, Key-Hwan, Baek, Kwang-Hyun, Sung, Jong-Hyuk, Park, Kyong Soo, Park, Sang Gyu
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Metabolism
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3829140/
https://ncbi.nlm.nih.gov/pubmed/24072712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.496331
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