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III. Cellular ultrastructures in situ as key to understanding tumor energy metabolism: biological significance of the Warburg effect

Despite the universality of metabolic pathways, malignant cells were found to have their metabolism reprogrammed to generate energy by glycolysis even under normal oxygen concentrations (the Warburg effect). Therefore, the pathway energetically 18 times less efficient than oxidative phosphorylation...

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Autors principals: Witkiewicz, Halina, Oh, Phil, Schnitzer, Jan E
Format: Artigo
Idioma:Inglês
Publicat: F1000Research 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3829121/
https://ncbi.nlm.nih.gov/pubmed/24358890
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12688/f1000research.2-10.v1
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