Platelets mediate increased endothelium permeability in dengue through NLRP3-inflammasome activation

Dengue is the most frequent hemorrhagic viral disease and re-emergent infection in the world. Although thrombocytopenia is characteristically observed in mild and severe forms of dengue, the role of platelet activation in dengue pathogenesis has not been fully elucidated. We hypothesize that platele...

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Hlavní autoři: Hottz, Eugenio D., Lopes, Juliana F., Freitas, Carla, Valls-de-Souza, Rogério, Oliveira, Marcus F., Bozza, Marcelo T., Da Poian, Andrea T., Weyrich, Andrew S., Zimmerman, Guy A., Bozza, Fernando A., Bozza, Patricia T.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Hematology 2013
Témata:
Plenary Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3829114/
https://ncbi.nlm.nih.gov/pubmed/24009231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2013-05-504449
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