Cross-talk between calcineurin/NFAT and Jak/STAT signalling induces cardioprotective αB-crystallin gene expression in response to hypertrophic stimuli

Among the stress proteins that are up-regulated in the heart due to imposed biomechanical stress, αB-crystallin (CryAB) is the most abundant and pivotal in rendering protection against stress-induced cell damage. Cardiomyocyte-specific expression of the CryAB gene was shown to be dependent upon an i...

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Hlavní autoři: Manukyan, Irena, Galatioto, Josephine, Mascareno, Eduardo, Bhaduri, Sikha, Siddiqui, MAQ
Médium: Artigo
Jazyk:Inglês
Vydáno: Blackwell Publishing Ltd 2010
Témata:
Original Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3829032/
https://ncbi.nlm.nih.gov/pubmed/19538478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1582-4934.2009.00804.x
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