Targeting histone deacetylases in pancreatic ductal adenocarcinoma

Pancreatic ductal adenocarcinoma (PDAC) is a dismal disease with a median survival below 6 months and a 5-year survival rate below 1%. Effective therapies for locally advanced or metastatic tumours are missing and curatively resected patients relapse in over 80% of the cases. Although histone deacet...

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Bibliographic Details
Main Authors: Schneider, Günter, Krämer, Oliver H, Fritsche, Petra, Schüler, Susanne, Schmid, Roland M, Saur, Dieter
Format: Artigo
Language:Inglês
Published: Blackwell Publishing Ltd 2010
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Reviews
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3828843/
https://ncbi.nlm.nih.gov/pubmed/19929947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1582-4934.2009.00974.x
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