An immunodominant La/SSB autoantibody proteome derives from public clonotypes

The La/SSB autoantigen is a major target of long-term humoral autoimmunity in primary Sjögren's Syndrome (SS) and systemic lupus erythematosus. A majority of patients with linked anti-Ro60/Ro52/La responses target an NH2-terminal epitope designated LaA that is expressed on Ro/La ribonucleoprote...

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Autors principals: Thurgood, L A, Arentz, G, Lindop, R, Jackson, M W, Whyte, A F, Colella, A D, Chataway, T K, Gordon, T P
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Science Inc 2013
Matèries:
Original Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3828827/
https://ncbi.nlm.nih.gov/pubmed/23841690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cei.12171
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