Interactions between the discoidin domain receptor 1 and β1 integrin regulate attachment to collagen

Collagen degradation by phagocytosis is essential for physiological collagen turnover and connective tissue homeostasis. The rate limiting step of phagocytosis is the binding of specific adhesion receptors, which include the integrins and discoidin domain receptors (DDR), to fibrillar collagen. Whil...

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Detalhes bibliográficos
Main Authors: Staudinger, Lisa A., Spano, Stephen J., Lee, Wilson, Coelho, Nuno, Rajshankar, Dhaarmini, Bendeck, Michelle P., Moriarty, Tara, McCulloch, Christopher A.
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3828761/
https://ncbi.nlm.nih.gov/pubmed/24244851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/bio.20135090
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