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Complementary carrier peptide synthesis: general strategy and implications for prebiotic origin of peptide synthesis.

A method for peptide synthesis is proposed based on a template-directed scheme that parallels that of the native ribosomal mechanism. In this procedure, peptide bond formation is facilitated by the juxtaposition of aminoacyl and peptidyl oligonucleotide carriers bound adjacent to one another on an o...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Walder, J A, Walder, R Y, Heller, M J, Freier, S M, Letsinger, R L, Klotz, I M
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1979
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC382874/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/284368/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.76.1.51
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