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Steroid diamine-nucleic acid interactions: partial insertion of dipyrandium between unstacked base pairs of the poly(dA-dT) duplex in solution.

We report on an NMR investigation of steroid diamine.nucleic acid complexes as a function of phosphate-to-drug ratios in aqueous solution in order to evaluate the structural and kinetic aspects of the binding of a nonintercalative drug to a synthetic DNA in solution. The nonexchangeable proton chemi...

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Detaylı Bibliyografya
Asıl Yazarlar: Patel, D J, Canuel, L L
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 1979
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC382868/
https://ncbi.nlm.nih.gov/pubmed/284337
Etiketler: Etiketle
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