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Antifungal mechanisms by which a novel Pseudomonas aeruginosa phenazine toxin kills Candida albicans in biofilms

Pseudomonas aeruginosa produces several phenazines including the recently described 5-methyl-phenazine-1-carboxylic acid (5MPCA), which exhibits a novel antibiotic activity towards pathogenic fungi such as Candida albicans. Here we characterize the unique antifungal mechanisms of 5MPCA using its ana...

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Detalhes bibliográficos
Main Authors: Morales, Diana K., Jacobs, Nicholas J., Rajamani, Sathish, Krishnamurthy, Malathy, Cubillos-Ruiz, Juan R., Hogan, Deborah A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3828654/
https://ncbi.nlm.nih.gov/pubmed/21143312
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2958.2010.07414.x
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