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Dynamin triple knockout cells reveal off target effects of commonly used dynamin inhibitors
Dynamin, which is encoded by three genes in mammals, is a GTPase implicated in endocytic membrane fission. Dynamin 1 and 3 are predominantly expressed in brain, whereas dynamin 2 is ubiquitously expressed. With the goal of assessing the impact of the lack of dynamin on cell physiology, we previously...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Company of Biologists
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3828596/ https://ncbi.nlm.nih.gov/pubmed/24046449 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.138578 |
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