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A new kind of membrane-tethered eukaryotic transcription factor that shares an auto-proteolytic processing mechanism with bacteriophage tail-spike proteins

MrfA, a transcription factor that regulates Dictyostelium prestalk cell differentiation, is an orthologue of the metazoan myelin gene regulatory factor (MRF) proteins. We show that the MRFs contain a predicted transmembrane domain, suggesting that they are synthesised as membrane-tethered proteins t...

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Bibliografische gegevens
Hoofdauteurs: Senoo, Hiroshi, Araki, Tsuyoshi, Fukuzawa, Masashi, Williams, Jeffrey G.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The Company of Biologists 2013
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3828593/
https://ncbi.nlm.nih.gov/pubmed/24046445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.133231
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