Genetic susceptibility to infectious disease in East African Shorthorn Zebu: a genome-wide analysis of the effect of heterozygosity and exotic introgression

BACKGROUND: Positive multi-locus heterozygosity-fitness correlations have been observed in a number of natural populations. They have been explained by the correlation between heterozygosity and inbreeding, and the negative effect of inbreeding on fitness (inbreeding depression). Exotic introgressio...

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Autori principali: Murray, Gemma GR, Woolhouse, Mark EJ, Tapio, Miika, Mbole-Kariuki, Mary N, Sonstegard, Tad S, Thumbi, Samuel M, Jennings, Amy E, van Wyk, Ilana Conradie, Chase-Topping, Margo, Kiara, Henry, Toye, Phil, Coetzer, Koos, deC Bronsvoort, Barend M, Hanotte, Olivier
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2013
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3828575/
https://ncbi.nlm.nih.gov/pubmed/24209611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2148-13-246
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