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Structural basis for targeting the chromatin repressor Sfmbt to Polycomb response elements

Polycomb group (PcG) protein complexes repress developmental regulator genes by modifying their chromatin. How different PcG proteins assemble into complexes and are recruited to their target genes is poorly understood. Here, we report the crystal structure of the core of the Drosophila PcG protein...

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Detalhes bibliográficos
Main Authors: Alfieri, Claudio, Gambetta, Maria Cristina, Matos, Raquel, Glatt, Sebastian, Sehr, Peter, Fraterman, Sven, Wilm, Matthias, Müller, Jürg, Müller, Christoph W.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3828522/
https://ncbi.nlm.nih.gov/pubmed/24186981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.226621.113
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