Dual regulation of Dmc1-driven DNA strand exchange by Swi5–Sfr1 activation and Rad22 inhibition

Both ubiquitously expressed Rad51 and meiosis-specific Dmc1 are required for crossover production during meiotic recombination. The budding yeast Rad52 and its fission yeast ortholog, Rad22, are “mediators;” i.e., they help load Rad51 onto ssDNA coated with replication protein A (RPA). Here we show...

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Detalles Bibliográficos
Main Authors: Murayama, Yasuto, Kurokawa, Yumiko, Tsutsui, Yasuhiro, Iwasaki, Hiroshi
Formato: Artigo
Idioma:Inglês
Publicado: Cold Spring Harbor Laboratory Press 2013
Assuntos:
Research Communication
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3828516/
https://ncbi.nlm.nih.gov/pubmed/24186976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.218693.113
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