Characterization of PfTrxR inhibitors using antimalarial assays and in silico techniques

BACKGROUND: The compounds 1,4-napthoquinone (1,4-NQ), bis-(2,4-dinitrophenyl)sulfide (2,4-DNPS), 4-nitrobenzothiadiazole (4-NBT), 3-dimethylaminopropiophenone (3-DAP) and menadione (MD) were tested for antimalarial activity against both chloroquine (CQ)-sensitive (D6) and chloroquine (CQ)-resistant...

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Detalhes bibliográficos
Main Authors: Munigunti, Ranjith, Gathiaka, Symon, Acevedo, Orlando, Sahu, Rajnish, Tekwani, Babu, Calderón, Angela I
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3828397/
https://ncbi.nlm.nih.gov/pubmed/24209891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1752-153X-7-175
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