Protection of nonobese diabetic mice from autoimmune diabetes by reduction of islet mass before insulitis.
Nonobese diabetic mice spontaneously develop diabetes that is caused by autoimmune cell-mediated destruction of pancreatic beta cells. Here we report that surgical removal of 90% of pancreatic tissue before onset of insulitis induced a long-term diabetes-free condition in nonobese diabetic mice. Pan...
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| Udgivet i: | Proc Natl Acad Sci U S A |
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| Principais autores: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
1996
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC38282/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8855307/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.20.11053 |
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