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Intracellular Interferons in Fish: A Unique Means to Combat Viral Infection
We demonstrate for the first time in vertebrates, that alternative splicing of interferon (IFN) genes can lead to a functional intracellular IFN (iIFN). Fish IFN genes possess introns and in rainbow trout three alternatively spliced transcripts of the IFN1 gene exist. Two of the encoded IFNs are pre...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3828176/ https://ncbi.nlm.nih.gov/pubmed/24244163 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1003736 |
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