Recruitment of TREX to the Transcription Machinery by Its Direct Binding to the Phospho-CTD of RNA Polymerase II

Messenger RNA (mRNA) synthesis and export are tightly linked, but the molecular mechanisms of this coupling are largely unknown. In Saccharomyces cerevisiae, the conserved TREX complex couples transcription to mRNA export and mediates mRNP formation. Here, we show that TREX is recruited to the trans...

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Detalhes bibliográficos
Main Authors: Meinel, Dominik M., Burkert-Kautzsch, Cornelia, Kieser, Anja, O'Duibhir, Eoghan, Siebert, Matthias, Mayer, Andreas, Cramer, Patrick, Söding, Johannes, Holstege, Frank C. P., Sträßer, Katja
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3828145/
https://ncbi.nlm.nih.gov/pubmed/24244187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1003914
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