Killer Immunoglobulin-like Receptors (KIR) haplogroups A and B track with Natural Killer Cells and Cytokine Profile in Aged Subjects: Observations from Octo/Nonagenarians in the Belfast Elderly Longitudinal Free-living Aging STudy (BELFAST)

BACKGROUND: Natural Killer Cells (NK) play an important role in detection and elimination of virus-infected, damaged or cancer cells. NK cell function is guided by expression of Killer Immunoglobulin-like Receptors (KIRs) and contributed to by the cytokine milieu. KIR molecules are grouped on NK cel...

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Detalhes bibliográficos
Main Authors: Rea, Irene Maeve, Maxwell, Lynn D, McNerlan, Susan E, Alexander, H Denis, Curran, Martin D, Middleton, Derek, Ross, Owen A
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3827941/
https://ncbi.nlm.nih.gov/pubmed/23957956
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4933-10-35
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