Dose escalation to high-risk sub-volumes based on non-invasive imaging of hypoxia and glycolytic activity in canine solid tumors: a feasibility study

INTRODUCTION: Glycolytic activity and hypoxia are associated with poor prognosis and radiation resistance. Including both the tumor uptake of 2-deoxy-2-[(18) F]-fluorodeoxyglucose (FDG) and the proposed hypoxia tracer copper(II)diacetyl-bis(N(4))-methylsemithio-carbazone (Cu-ATSM) in targeted therap...

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Dettagli Bibliografici
Autori principali: Clausen, Malene M, Hansen, Anders E, af Rosenschold, Per Munck, Kjær, Andreas, Kristensen, Annemarie T, McEvoy, Fintan J, Engelholm, Svend A
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2013
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3827870/
https://ncbi.nlm.nih.gov/pubmed/24199939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1748-717X-8-262
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