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FGF2 modulates cardiac remodeling in an isoform- and sex-specific manner

Pathological cardiac hypertrophy and cardiac fibrosis are remodeling events that result in mechanical stiffness and pathophysiological changes in the myocardium. Both humans and animal models display a sexual dimorphism where females are more protected from pathological remodeling. Fibroblast growth...

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Autors principals: Nusayr, Eyad, Sadideen, Doraid Tarek, Doetschman, Tom
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Publishing Ltd 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3827774/
https://ncbi.nlm.nih.gov/pubmed/24244869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/phy2.88
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