Downregulation of the H-2K(d) gene by siRNA affects the cytotoxicity of murine LAK cells

To investigate the effect of the H-2K(d) gene on the lymphocyte membrane, we constructed a small interfering RNA (siRNA) that targets the H-2K(d) gene and compared the cytotoxicity of mouse lymphokine-activated killer (LAK) cells with different H-2K(d) expression states. H-2K(d)-targeting siRNA was...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Liu, Xin, Cui, Xin, Shan, Ningning, Li, Ying, Fang, Xiaosheng, Ding, Mei, Wang, Xin
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2013
Sujets:
Primary Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3827616/
https://ncbi.nlm.nih.gov/pubmed/24206544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2867-13-112
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