Fas (CD95) expression and death-mediating function are induced by CD4 cross-linking on CD4+ T cells.

The CD4 receptor contributes to T-cell activation by coligating major histocompatibility complex class II on antigen presenting cells with the T-cell receptor (TCR)/CD3 complex, and triggering a cascade of signaling events including tyrosine phosphorylation of intracellular proteins. Paradoxically,...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Desbarats, J, Freed, J H, Campbell, P A, Newell, M K
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 1996
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC38275/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8855300/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.20.11014
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