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Role of Tumor Necrosis Factor-α in the Human Systemic Endotoxin-Induced Transcriptome

TNFα has been implicated in the pathogenesis of various inflammatory diseases. Different strategies to inhibit TNFα in patients with sepsis and chronic inflammatory conditions have shown contrasting outcomes. Although TNFα inhibitors are widely used in clinical practice, the impact of TNFα antagonis...

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Détails bibliographiques
Auteurs principaux: Scicluna, Brendon P., van 't Veer, Cornelis, Nieuwdorp, Max, Felsmann, Karen, Wlotzka, Britta, Stroes, Erik S. G., van der Poll, Tom
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3827317/
https://ncbi.nlm.nih.gov/pubmed/24236088
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0079051
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