The Effect of Factor VIII Deficiencies and Replacement and Bypass Therapies on Thrombus Formation under Venous Flow Conditions in Microfluidic and Computational Models

Clinical evidence suggests that individuals with factor VIII (FVIII) deficiency (hemophilia A) are protected against venous thrombosis, but treatment with recombinant proteins can increase their risk for thrombosis. In this study we examined the dynamics of thrombus formation in individuals with hem...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Onasoga-Jarvis, Abimbola A., Leiderman, Karin, Fogelson, Aaron L., Wang, Michael, Manco-Johnson, Marilyn J., Di Paola, Jorge A., Neeves, Keith B.
التنسيق: Artigo
اللغة:Inglês
منشور في: Public Library of Science 2013
الموضوعات:
Research Article
الوصول للمادة أونلاين:https://ncbi.nlm.nih.gov/pmc/articles/PMC3827262/
https://ncbi.nlm.nih.gov/pubmed/24236042
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0078732
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