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Agnogene Deletion in a Novel Pathogenic JC Virus Isolate Impairs VP1 Expression and Virion Production

Infection of glial cells by the human polyomavirus JC (JCV) causes progressive multifocal leukoencephalopathy (PML). JCV Encephalopathy (JCVE) is a newly identified disease characterized by JCV infection of cortical pyramidal neurons. The virus JCV(CPN) associated with JCVE contains a unique 143 bas...

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Detalhes bibliográficos
Main Authors: Ellis, Laura C., Norton, Elizabeth, Dang, Xin, Koralnik, Igor J.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3827225/
https://ncbi.nlm.nih.gov/pubmed/24265839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0080840
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