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Beneficial Role of Rapamycin in Experimental Autoimmune Myositis

INTRODUCTION: We developed an experimental autoimmune myositis (EAM) mouse model of polymyositis where we outlined the role of regulatory T (Treg) cells. Rapamycin, this immunosuppressant drug used to prevent rejection in organ transplantation, is known to spare Treg. Our aim was to test the efficac...

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Bibliografiske detaljer
Main Authors: Prevel, Nicolas, Allenbach, Yves, Klatzmann, David, Salomon, Benoit, Benveniste, Olivier
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3827074/
https://ncbi.nlm.nih.gov/pubmed/24265670
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0074450
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