Effects of Bone Marrow-Derived Mesenchymal Stem Cells on the Axonal Outgrowth through Activation of PI3K/AKT Signaling in Primary Cortical Neurons Followed Oxygen-Glucose Deprivation Injury

BACKGROUND: Transplantation with bone marrow-derived mesenchymal stem cells (BMSCs) improves the survival of neurons and axonal outgrowth after stroke remains undetermined. Here, we investigated whether PI3K/AKT signaling pathway is involved in these therapeutic effects of BMSCs. METHODOLOGY/PRINCIP...

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Detalhes bibliográficos
Main Authors: Liu, Yong, Zhang, Yixian, Lin, Longzai, Lin, Feifei, Li, Tin, Du, Houwei, Chen, Ronghua, Zheng, Wei, Liu, Nan
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3827028/
https://ncbi.nlm.nih.gov/pubmed/24265694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0078514
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