The perivascular niche regulates breast tumor dormancy

In a significant fraction of breast cancer patients, distant metastases emerge after years or even decades of latency. How disseminated tumor cells (DTCs) are kept dormant, and what ‘wakes them up’, are fundamental problems in tumor biology. To address these questions, we utilized metastasis assays...

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Bibliografiske detaljer
Main Authors: Ghajar, Cyrus M., Peinado, Héctor, Mori, Hidetoshi, Matei, Irina R., Evason, Kimberley J., Brazier, Hélène, Almeida, Dena, Koller, Antonius, Hajjar, Katherine A., Stainier, Didier Y.R., Chen, Emily I., Lyden, David, Bissell, Mina J.
Format: Artigo
Sprog:Inglês
Udgivet: 2013
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3826912/
https://ncbi.nlm.nih.gov/pubmed/23728425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb2767
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