Fibroblast Growth Factor-2 and Bone Morphogenetic Protein-2 Have a Synergistic Stimulatory Effect on Bone Formation in Cell Cultures From Elderly Mouse and Human Bone

Combined regimens of fibroblast growth factor-2 (FGF-2) and bone morphogenetic protein-2 (BMP-2) were investigated to stimulate osteogenic differentiation. In young mouse calvaria-derived cells, FGF-2 (0.16ng/mL) in combination with BMP-2 (50ng/mL) did not enhance mineralization, but in old mouse ce...

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Detalhes bibliográficos
Main Authors: Kuhn, Liisa T., Ou, Guomin, Charles, Lyndon, Hurley, Marja M., Rodner, Craig M., Gronowicz, Gloria
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2013
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3826858/
https://ncbi.nlm.nih.gov/pubmed/23531867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/gerona/glt018
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