Release of tissue inhibitor of metalloproteinase-2 from alginate microcapsule encapsulating genetically engineered cells

BACKGROUND: In this study, 293T cells were genetically engineered to secrete tissue inhibitor of metalloproteinase-2 (TIMP2) and encapsulated into alginate microcapsules to continuously release TIMP2 protein. METHODS: The anti-invasive potential of the microcapsules was studied in vitro using brain...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Kim, Yeon Seong, Jeong, Young-II, Jin, Shu-Guang, Pei, Jian, Wen, Min, Kim, In-Young, Moon, Kyung-Sub, Jung, Tae-Young, Ryu, Hyang-Hwa, Jung, Shin
Format: Artigo
Sprache:Inglês
Veröffentlicht: Dove Medical Press 2013
Schlagworte:
Original Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3826773/
https://ncbi.nlm.nih.gov/pubmed/24231999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S52577
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