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Different Desensitization Patterns for Sensory and Vascular TRPV1 Populations in the Rat: Expression, Localization and Functional Consequences

BACKGROUND AND PURPOSE: TRPV1 is expressed in sensory neurons and vascular smooth muscle cells, contributing to both pain perception and tissue blood distribution. Local desensitization of TRPV1 in sensory neurons by prolonged, high dose stimulation is re-engaged in clinical practice to achieve anal...

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Detalhes bibliográficos
Main Authors: Czikora, Ágnes, Rutkai, Ibolya, Pásztor, Enikő T., Szalai, Andrea, Pórszász, Róbert, Boczán, Judit, Édes, István, Papp, Zoltán, Tóth, Attila
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3826751/
https://ncbi.nlm.nih.gov/pubmed/24250792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0078184
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