Combination of Arsenic and Interferon-α Inhibits Expression of KSHV Latent Transcripts and Synergistically Improves Survival of Mice with Primary Effusion Lymphomas

BACKGROUND: Kaposi sarcoma-associated herpesvirus (KSHV) is the etiologic agent of primary effusion lymphomas (PEL). PEL cell lines infected with KSHV, but negative for Epstein-Barr virus have a tumorigenic potential in non-obese diabetic/severe combined immunodeficient mice and result in efficient...

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Detalhes bibliográficos
Main Authors: El Hajj, Hiba, Ali, Jihane, Ghantous, Akram, Hodroj, Dana, Daher, Ahmad, Zibara, Kazem, Journo, Chloé, Otrock, Zaher, Zaatari, Ghazi, Mahieux, Renaud, El Sabban, Marwan, Bazarbachi, Ali, Abou Merhi, Raghida
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3826709/
https://ncbi.nlm.nih.gov/pubmed/24250827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0079474
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